Journal Publications
Thomford N.E., Bope C.D., Agamah F.E., Dzobo K., Owusu Ateko R., Chimusa E., Mazandu G.K., Ntumba S..B, Dandara C., Wonkam A. Implementing Artificial Intelligence and Digital Health in Resource-Limited Settings? Top 10 Lessons We Learned in Congenital Heart Defects and Cardiology. OMICS. doi: 10.1089/omi.2019.0142
Dzobo K., Thomford N.E., Senthebane D.A. Targeting the Versatile Wnt/β-Catenin Pathway in Cancer Biology and Therapeutics: From Concept to Actionable Strategy. OMICS. 23(11):517-538. doi: 10.1089/omi.2019.0147.
Dzobo K., Adotey S., Thomford N.E., Dzobo W. Integrating Artificial and Human Intelligence: A Partnership for Responsible Innovation in Biomedical Engineering and Medicine. OMICS: A journal of integrative biology.2019, 23 DOI: 10.1089/omi.2019.0038
Agamah F.E., Mazandu G.K., Hassan R., Thomford N.E, Ghansah A., Chimusa E.R. Computational / in silico methods in drug target and leads prediction. Brief Bioinform. pii: bbz103. doi: 10.1093/bib/bbz103.
Dandara C., Thomford N.E., Tashinga E.B. Herbal Remedies: Throwing Off Phenotype Prediction—A Culprit for Pharmacogenomic‐Guided Drug Therapy and Drug Safety. Clin Pharmacol Ther. doi: 10.1002/cpt.1509
Ndadza A., Thomford N.E., Mukanganyama S., Wonkam A., Ntsekhe M., Dandara C. The Genetics of Warfarin Dose–Response Variability in Africans: An Expert Perspective on Past, Present, and Future. OMICS: A Journal of Integrative Biology. 2019, 23(3), 152-166
Awany D., Allali I., Dalvie S., Hemmings S., Mwaikono K.S., Thomford N.E., Gomez A., Mulder N. and Chimusa E.R. Host and Microbiome Genome-Wide Association Studies: Current State and Challenges. Front. Genet. 2019. 9:637. doi: 10.3389/fgene.2018.00637
Senthebane, D.A., Jonker, T., Rowe, A., Thomford, N.E., Munro, D., Dandara, C., Wonkam, A., Govender, D., Calder, B., Soares, N.C., Blackburn, J.M., Parker, M.I., Dzobo, K. The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices. Int. J. Mol. Sci. 2018, 19, 2861
Dzobo K., Thomford N.E., Senthebane D., Shipanga H., Rowe A., Dandara C., Pillay M. Motaung K. Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine. Stem Cells international. 2018 volume 2018, Article ID 2495848 https://doi.org/10.1155/2018/2495848
Thomford N.E., Senthebane D., Rowe A., Munro D., Seele P., Maroyi A., Dzobo K. Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery. Int J Mol Sci. 2018 25;19(6). doi: 10.3390/ijms19061578.
Kuguyo O., Tsikai N., Thomford N.E., Magwali T., Madziyire M.G., Nhachi F.B.C., Matimba A., Dandara C. Genetic susceptibility for cervical cancer in African populations: what are the host genetic drivers? OMICS: A Journal of Integrative Biology 2018 22(7):468-483. doi: 10.1089/omi.2018.0075
Thomford N.E., Dzobo K., Chimusa E., Andrae-Marobela K., Chirikure S., Wonkam A., Dandara C. Personalized herbal medicine? A roadmap for convergence of herbal and precision medicine biomarker innovations? OMICS: A Journal of Integrative Biology. 2018. 22(6): 375-391
Thomford N.E., Dzobo K., Yao N.A., Chimusa E., Evans J., Okai E., Kruszka P, Muenke M., Awandare G., Wonkam A., Dandara C. Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa. OMICS: A Journal of Integrative Biology. 2018, 22 (5):301-321. DOI: 10.1089/omi.2018.0033
Dzobo K., Hassen N., Senthebane D.A., Thomford N.E., Rowe A., Shipanga H., Wonkam A., Parker M.I., Mowla S., Dandara C. Chemoresistance to cancer treatment: Benzo-α-pyrene as friend or foe? Molecules 2018, 23 (24) 930; doi:10.3390/molecules23040930
Dzobo K., Senthebane D. A., Thomford N.E., Rowe A., Dandara C., Parker M.I. Not Everyone Fits the Mold: Intratumor and Intertumor Heterogeneity and Innovative Cancer Drug Design and Development. OMICS: A Journal of Integrative Biology. 2018, 22(1): 17-34
Thomford N.E., Dzobo, K., Adu, F., Chirikure S., Wonkam, A., D., Dandara. Bush mint (Hyptis suaveolens) and Spreading Hogweed (Boerhavia diffusa) medicinal plant extracts differentially affect activities of CYP1A2, CYP2D6 and CYP3A4 enzymes. J Ethnopharmacol.2017. 21; 211:58-69
Senthebane D.A., Rowe A., Thomford N.E., Shipanga H., Munro, D., Al Mazeedi M.A.M., Almazyadi H.A.M., Kallmeyer K., Dandara C., Pepper, Parker, M.I., Dzobo, K. The role of tumor microenvironment in chemoresistance: To survive, keep your enemies close. Int. J. Mol. Sci. 2017, 18, 1586; doi:10.3390/ijms18071586
Dzobo K., Senthebane D. A., Rowe A., Thomford N.E., Mwapagha L.M., Al-Awwad N., Dandara C., Parker M.I. (2016). Cancer Stem Cell Hypothesis for Therapeutics Innovation in Oncology? Taking the Root out, not chopping the Leaf. OMICS: A Journal of Integrative Biology; 20(12) ,681-691
Thomford N.E, Mkhezi B., Dzobo K., Mpye K., Rowe A., Parker M.I., Wonkam A., Skelton M., September A.V., Dandara C. African lettuce (Launaea taraxacifolia) displays possible anti-cancer effects and herb-drug interaction potential via CYP1A2, CYP2C9 and CYP2C19 inhibition. OMICS: A Journal of Integrative Biology 2016; 20(9),528-37
Dzobo K., Turnley T., Wishart A., Rowe A., Kallmeyer K., van Vollenstee F.A., Thomford N.E., Dandara C., Chopera D., Pepper M.S., M. Iqbal Parker M.I. Fibroblast-Derived Extracellular Matrix Induces Chondrogenic Differentiation in Human Adipose-Derived Mesenchymal Stromal/Stem Cells in Vitro. Int. J. Mol. Sci. 2016, 17, 1259; doi:10.3390/ijms17081259
Thomford N.E., Dzobo, K., Chopera, D., Wonkam, A., Maroyi, A., Blackhurst, D., Dandara. In vitro reversible and time-dependent inhibition of medicinal herbal plant extracts Newbouldia laevis and Cassia abbreviata: Implications for Herb-Drug Interactions. Molecules, 2016, 21, 891, 1-19.
Thomford N.E., Awortwe, C., Dzobo, K., Adu, F., Chopera, D., Wonkam, A., Skelton, M., Blackhurst, D., Dandara. C. Inhibition of CYP2B6 by Medicinal Plant Extracts: Implication for the use of Efavirenz and Nevirapine-based Highly Active Anti-Retroviral Therapy (HAART) in Resource-Limited Settings. Molecules, 2016, 21, 211; doi:10.3390/molecules21020211
Dzobo K., Vogelsang M, Thomford N.E., Dandara C., Kallmeyer K., Pepper M.S., Parker M.I. Wharton’s Jelly-derived mesenchymal stromal cells and fibroblast-derived extracellular matrix synergistically activate apoptosis in a p21-dependent mechanism in WHCO1 and MDA MB 231 cancer cells in vitro. Stem Cells International, vol. 2016, Article ID 4842134, 17 pages, 2016. doi:10.1155/2016/4842134
Thomford N.E., Dzobo K., Chopera D., Wonkam A., Skelton M., Blackhurst,D., Chirikure S., Dandara C. Pharmacogenomics Implications of Using Herbal Medicinal Plants on African Populations in Health Transition. Pharmaceuticals 2015, 8, 637-663.
Book Chapter
Dzobo K, Thomford NE, Rowe A, Senthebane DA and Dandara C (2019). Single cell Omics: Deciphering tumor clonal architecture: In Single-Cell Omics: Technological Advances and Applications. Elsevier publishers DOI: 10.1016/B978-0-12-814919-5.00005-1